ATF2 anticorps (AA 93-450)
Aperçu rapide pour ATF2 anticorps (AA 93-450) (ABIN3029845)
Antigène
Voir toutes ATF2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 93-450
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Purification
- Antigen affinity
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Immunogène
- Human partial recombinant protein (AA 93-450) was used as the immunogen for this ATF2 antibody.
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Isotype
- IgG
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the ATF2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells
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Restrictions
- For Research Use only
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- -20 °C
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Stockage commentaire
- After reconstitution, the ATF2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- ATF2 (Activating Transcription Factor 2 (ATF2))
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Autre désignation
- ATF2
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Sujet
- Activating transcription factor 2 is a protein that in humans is encoded by the ATF2 gene. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA-binding proteins. It binds to the cAMP-responsive element (CRE), an octameric palindrome. ATF2 forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. It is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus, it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.
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ID gène
- 1386
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Pathways
- Signalisation MAPK, Signalisation RTK, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
Antigène
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